This article discusses Zoloft withdrawal symptoms, their duration, and when to consult a doctor. Zoloft (sertraline) withdrawal symptoms typically last up to 1 to 2 weeks, but may last even longer in some people. You should avoid abruptly stopping sertraline treatment unless otherwise directed by your healthcare provider. If your symptoms are physical, come on suddenly, and start within days of stopping Zoloft, they are probably withdrawal. If your symptoms are mostly emotional and keep getting worse, it could be a relapse. People who stop taking the antidepressant sertraline may experience withdrawal symptoms. Learn about withdrawal timeline, prevention, and how to manage symptoms. Some people refer to antidepressant discontinuation syndrome as “antidepressant withdrawal.” The syndrome usually isn’t physically harmful, but it can be very unpleasant. In addition, stopping an antidepressant can make the condition it was treating (like depression or anxiety) come back. Withdrawal after only 2-3 days of Zoloft is not that long, for me it lasted 2-3 days but recovery from a major anxiety event is (think from 1 week to few months). In this guide, we’ll walk you through what happens when you stop taking Zoloft, common discontinuation symptoms and timelines, how to tell withdrawal apart from relapse, and how to stop Zoloft safely with your provider’s help. Learn what Zoloft withdrawal feels like, when symptoms start, how long they last, and what helps. Expert guidance for a safer transition. Stopping Zoloft suddenly can cause intense withdrawal symptoms, including dizziness, nausea, brain zaps, anxiety, and mood swings. In some cases, symptoms can be severe enough to interfere with daily life and may last for weeks. Discontinuing Zoloft (sertraline) can cause withdrawal symptoms, so a gradual dose reduction is recommended when stopping this treatment. Read here for withdrawal symptoms and timelines for Zoloft.